Jacksonville Jaguars 26, San Francisco 49ers 21 · Sep 28, 2025 · statshawk

NFLScores

football game fileFinal

Jacksonville Jaguarsaway

26

at

San Francisco 49ershome

21

Sun, Sep 28, 2025, 4:05 PM EDTLevi's Stadium · Santa Clara · USA

Comparison

Side by side.

Final

Away

Jacksonville Jaguars

Score

26

Home

San Francisco 49ers

Score

21

Key performers

Brock Purdy309 PASS YDS · 2 PASS TD Trevor Lawrence174 PASS YDS · 1 PASS TD