San Francisco 49ers 41, Arizona Cardinals 22 · Nov 16, 2025 · statshawk

NFLScores

football game fileFinal

San Francisco 49ersaway

41

at

Arizona Cardinalshome

22

Sun, Nov 16, 2025, 4:05 PM ESTState Farm Stadium · Glendale · USA

Comparison

Side by side.

Final

Away

San Francisco 49ers

Score

41

Home

Arizona Cardinals

Score

22

Key performers

Jacoby Brissett452 PASS YDS · 2 PASS TD Brock Purdy200 PASS YDS · 3 PASS TD